Contraline Inc.  logo
Biotech/Pharma

Contraline Inc.

Contraline is a Charlottesville-based company working at the forefront of reproductive medicine.

CORE INFO

$92.5M
Total Funding
Series B
Round
2015
Founded
27
Team Size
Charlottesville, Virginia, United States
Headquarters

Contraline Inc. is a biotechnology company developing male contraceptive solutions, including a topical gel and a reversible implant, aimed at providing safe and effective options for men and couples.

  • Contraline recently secured $92.5 million in a Series B funding round, co-led by BVF Partners L.P. and RA Capital Management, with participation from GV, Lumira Ventures, and Invus.businesswire.com
  • The company's NES/T Gel has completed a global Phase 2b clinical trial with 462 couples, showing promising results in efficacy and user acceptability.businesswire.com

WHY WE WOULD WORK AT CONTRALINE INC.

Empower Reproductive Health

Join a mission-driven team dedicated to providing innovative male contraceptive solutions that enhance personal freedom and control in reproductive health.

Cutting-Edge Technology

Work with groundbreaking products like NES/T Gel and the ADAM™ implant, pushing the boundaries of male contraception through advanced biotechnology.

Collaborative Team Culture

Be part of a growing team of 27 passionate professionals, fostering a collaborative environment that values innovation and creativity.

Strong Financial Backing

Benefit from the security of a well-funded company, having raised $113.98 million, including a recent $92.5 million Series B round to fuel growth.

Clinical Success Stories

Contribute to impactful clinical trials, including a successful Phase 2b trial with 462 couples, showcasing the efficacy and acceptability of NES/T Gel.

Innovative Work Environment

Engage in a culture that prioritizes innovation, encouraging new ideas and solutions in the rapidly evolving field of male contraception.

MARKET AND TRACTION

TOTAL FUNDING

✦ KEY METRIC
  • Raised a total of $113.98 million across 14 funding rounds.

  • The latest funding round was a Series B round of $92.5 million announced in June 2026, co-led by BVF Partners L.P. and RA Capital Management.
  • TEAM GROWTH

    ✦ KEY METRIC
  • The company has expanded its team from 7 employees at the end of 2021 to approximately 27 employees as of now.

  • This growth reflects the company's increasing operational capacity as it prepares for Phase 3 clinical development.
  • CLINICAL TRIAL SUCCESS

    ✦ KEY METRIC
  • NES/T Gel has completed a global Phase 2b clinical trial involving 462 couples, demonstrating promising results in efficacy and user acceptability.

  • The company is preparing to enter Phase 3 clinical development in 2027, indicating strong progress in its product pipeline.
  • MARKET POSITION

  • Contraline Inc. is positioned as a pioneer in the male contraceptive market, focusing on innovative solutions that emphasize safety and reversibility.

  • The company's flagship product, NES/T Gel, aims to provide a new contraceptive option for men, addressing a significant gap in reproductive health solutions.
  • MISSION STATEMENT

  • Contraline's mission is to develop effective, safe, and reversible contraceptive options for men and couples worldwide.

  • The company emphasizes innovation and personal freedom in reproductive health, aiming to empower users in their contraceptive choices.
  • PRODUCT AND TECH

    NES/T Gel

    NES/T Gel is an investigational topical gel that combines synthetic progestin segesterone acetate with testosterone to suppress sperm production while maintaining physiological testosterone levels. This innovative product has completed a Phase 2b clinical trial with promising results, paving the way for its anticipated Phase 3 development in 2027.

    ADAM™ Implant

    ADAM™ is a long-lasting, non-hormonal, and reversible contraceptive implant currently in clinical trials. This innovative technology aims to provide an alternative contraceptive solution that does not rely on hormonal methods, expanding options for male contraception.

    Hydrogel-based Technology

    Contraline is developing hydrogel-based implants as part of its contraceptive solutions. This technology is crucial for creating effective, long-lasting, and reversible male contraceptive options that can integrate seamlessly into users' lives.

    Clinical Development Expertise

    Contraline's expertise in clinical development is demonstrated through its successful Phase 2b trial for NES/T Gel and ongoing trials for ADAM™. This experience is vital for advancing innovative male contraceptive solutions and ensuring their safety and efficacy.

    Funding for Innovation

    With a total of $113.98 million raised across multiple funding rounds, including a recent $92.5 million Series B, Contraline is well-positioned to advance its research and development efforts. This financial backing supports the company's mission to innovate in male reproductive health.

    COMPANY CULTURE

    Values

  • Commitment to innovation in male contraception

  • Focus on providing safe and reversible contraceptive options

  • Emphasis on personal freedom and control in reproductive health

  • Dedication to improving the lives of men and couples worldwide
  • Operating Principles

  • Foster a collaborative and inclusive work environment

  • Encourage open communication and transparency

  • Prioritize ethical practices in research and development

  • Strive for excellence in clinical trials and product development
  • Benefits

  • Opportunity to work on groundbreaking contraceptive solutions

  • Support for professional development and growth

  • Flexible work arrangements to promote work-life balance

  • Competitive compensation and benefits package
  • Learning & Growth

  • Continuous learning opportunities through workshops and training

  • Encouragement of innovative thinking and problem-solving

  • Access to mentorship from experienced leaders in biotechnology

  • Participation in industry conferences and networking events
  • Team Cadence

  • Regular team meetings to align on goals and progress

  • Collaborative project-based work to enhance teamwork

  • Feedback sessions to foster personal and professional growth

  • Celebrations of milestones and achievements to build camaraderie
  • HIRING SIGNAL

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    Net new roles in the last 90 days
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    90-Day VelocityV2 · BACKFILL
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    KEY COMPANY ANNOUNCEMENTS

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    8 announcements · ranked by importance
    Jun 10, 2026FUNDINGForm D filing — Contraline, Inc. (CIK 0001818752)sec.gov
    Jun 2, 2026FUNDINGContraline Announces $92.5 Million Series B Financing to Advance NES/T Male Contraceptive into Late-Stage Developmentbusinesswire.com
    Jun 2, 2026FUNDINGContraline Announces $92.5 Million Series B Financing to Advance NES/T Male Contraceptive into Late-Stage Development | VirginiaBiovabio.org
    Apr 5, 2022FUNDINGForm D filing — Contraline, Inc. (CIK 0001818752)sec.gov
    Oct 1, 2021FUNDINGContraline Raises $10M in Series A Funding - FinSMEsfinsmes.com
    Mar 30, 2022EXEC HIREContraline Appoints Medical Device Industry Leader Dr. Yelena Tropsha as Chief Technology Officerbusinesswire.com
    Feb 24, 2022AWARDContraline’s Male Contraceptive Technology Wins ‘Best Innovation’ at Reproductive Health Innovation Summitbusinesswire.com
    Oct 1, 2023PRESSCompany Leadershipcontraline.com